Houses are the places where people spend most of their time. That is why indoor air quality at home is essential for public health. Sufficient ventilation is the factor to avoid accumulation of pollutants in indoor air, which include microorganisms, such as SARS-CoV-2. Therefore, adequate ventilation is needed to provide good indoor air quality for human health and reduce infection risk at home. There are no reports of residential ventilation rates in Turkey. In this study, CO2 concentrations were measured in two residences in Izmir, Turkey. Three experiments were conducted to determine background concentrations and the rate of natural ventilation with infiltration and opening windows. Results show that air exchange provided by infiltration is low for both case rooms, while adequate ventilation could be achieved with natural ventilation under the studied conditions. Infiltration provided air exchange and ventilation rates of 0.18 h-1 and 5.9 m3/h for Case 1 and 0.29 h-1 and 8.23 m3/h for Case 2, respectively. Air exchange and ventilation rates were increased to 2.36 h-1 and 76.9 m3/h for Case 1 and 1.2 h-1 and 34 m3/h for Case 2, respectively, by opening the windows. Although ventilation can be provided by opening the windows, the other factors that determine its rate, e.g., meteorological variables, cannot be controlled by the occupants. Consequently, people cannot ensure the good indoor air quality in bedrooms and sufficient reduction in transmission of pathogenic microorganisms; therefore, risk of spreading diseases such as COVID-19 at home.